[exim] Exim with TMDA and virtual hosts

Has anyone setup TMDA with exim using virtual hosts? For instance, I
have my virtual users setup as /srv/mail/[domain]/[user] and want to use
TMDA and per-virtual-user configurations (ie. each user has a Maildir so
I'd like the TMDA configs to be in /srv/mail/[domain]/[user]/.tmda/). I
plan to build a web interface to manage the settings in TMDA (not for
all the features of TMDA (yet) but just a simple "yes i want to use
TMDA" type thing that would create the configs and their key).

I've done some poking around and I can see some tutorials on using TMDA
with exim... that's no problem. I was wondering specifically about
virtual users. I could probably bang my way through it but was
wondering if someone had already done this with some tips to share. =)

To make matters even more interesting, I also have a mailman setup with
some various mailing lists and wouldn't mind putting TMDA in front of
them (I remember doing this years ago with qmail and ezmlm-idx) just so
that any mails going to the mailing list from unsubscribed individuals
will get challenged (and thus likely not end up in my moderator queue).

Any tips would be appreciated.

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{FEE30AD4 : 7F6C A60C 06C2 4811 FA1C A2BC 2EBC 5E32 FEE3 0AD4}
mysql> SELECT * FROM users WHERE clue > 0;
Empty set (0.00sec)