On 10 Feb 2015, at 15:37, Brian Rudy <brian@???> wrote: > I may be missing the boat entirely here but it seems to me that this machine isn't reading the password file correctly.
SELinux getting its paws in the way, perhaps?
Try 'setenforce 0' as root, then restart Exim and try again. If it works then SELinux is your barrier and you'll need to make a judgement of whether you need it (and therefore need to create a new policy for the files in question) or not (with the attendant risks).