[exim] An error message that elludes me

On one system where we run exm -- actually a main mail server -- wer are
seeing in thed logs the messages

2015-01-13 16:22:27 1YAOJU-0007LQ-63 apple.cm [17.172.224.29] Connection
timed out
2015-01-13 16:22:27 1YAOJU-0007LQ-63 Berkeley DB error: page 1: illegal
page type or format
2015-01-13 16:22:27 1YAOJU-0007LQ-63 Berkeley DB error: PANIC: Invalid
argument
2015-01-13 16:22:27 1YAOJU-0007LQ-63 Berkeley DB error:
/var/spool/exim/db/retry: pgin failed for page 1
2015-01-13 16:22:27 1YAOJU-0007LQ-63 Berkeley DB error: PANIC: fatal
region error detected; run recovery
2015-01-13 16:22:27 1YAOJU-0007LQ-63 Berkeley DB error: PANIC: fatal
region error detected; run recovery

Ths appears often, and as far as I can tell on undeliverable mail. Where
should we be looking to fix this? Exim 4.85 now self built on OpenSuSE
11.4

Or is this a db error?

==John ff