[exim] Exim Access list

hello all;
I am new to exim,
I have exim mail relay service for some mail servers (these mail servers
have specific IP's and serve specific domains), my question can we make a
condition in exim configuration to allow just messages which has these pairs
(host ip +domain), i mean if one mail server has ip :1.1.1.1 and server two
domains x.y.z and x1.y1.z1, can we deny the messages come from 1.1.1.1 and
server domain n.m.y

Best Regards
Mustafa