[exim] 550-errors verification failed... unrouteable address…

Im very new to this . Mail isnt going out from various php applicitons

ive got this far

router input # exim -d -bvs my.name@???
Exim version 4.50 uid=0 gid=0 pid=10320 D=fbb95cfd
Berkeley DB: Sleepycat Software: Berkeley DB 4.2.52: (December 3, 2003)
Support for: iconv() IPv6 PAM Perl TCPwrappers OpenSSL
Lookups: lsearch wildlsearch nwildlsearch iplsearch cdb dbm dbmnz dsearch
ldap ldapdn ldapm mysql passwd pgsql
Authenticators: cram_md5 plaintext spa
Routers: accept dnslookup ipliteral manualroute queryprogram redirect
Transports: appendfile/maildir/mailstore autoreply pipe smtp
Fixed never_users: 0
changed uid/gid: forcing real = effective
uid=0 gid=0 pid=10320
auxiliary group list: <none>
configuration file is /etc/exim/exim.conf
log selectors = 00000ffc 00020800
trusted user
admin user
changed uid/gid: privilege not needed
uid=8 gid=12 pid=10320
auxiliary group list: <none>
originator: uid=0 gid=0 login=root name=root
sender address = root@???
Verifying: uid=8 gid=12 euid=8 egid=12
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
Verifying my.name@???
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
Considering my.name@???
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
routing my.name@???
--------> send_to_gateway router <--------
local_part=my.name domain=uni.ac.uk
calling send_to_gateway router
send_to_gateway router called for my.name@???
domain = uni.ac.uk
route_item = smtp.isp.co.uk
uni.ac.uk in "smtp.isp.co.uk"? no (end of list)
send_to_gateway router declined for my.name@???
--------> system_aliases router <--------


not sure how to fix it ....